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The proteomic change of GES1 infected by Helicobacter pylori OMVs

ABSTRACT: We investigated the effect of H.pylori OMVs on cellular events by detecting proteomic changes in GES1 cells. GES1 cells cocultured with increasing concentrations of H.pylori OMVs were subjected to quantitative proteomic analyses using label-free methods for relative quantitation.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

SUBMITTER: Sisi Wei

LAB HEAD: Lianmei Zhao

PROVIDER: PXD025259 | Pride | 2022-02-14

REPOSITORIES: Pride

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Outer Membrane Vesicles Secreted by Helicobacter pylori Transmitting Gastric Pathogenic Virulence Factors.

Wei Sisi S Li Xiaoya X Wang Jingjing J Wang Yaojie Y Zhang Cong C Dai Suli S Wang Xian X Deng Xiaoqing X Zhao Lianmei L Shan Baoen B

ACS omega 20211228 1

Helicobacter pylori (H. pylori) is known to be a major pathogen causing gastric diseases through its direct localization in gastric epithelium cells. H. pylori releases outer membrane vesicles (OMVs) throughout the growth process. The content, function, and mechanism of H. pylori OMVs in gastric epithelial cells remain unclear. In this study, we extracted and characterized H. pylori OMVs of two strains (standard strain NCTC11637 and clinical strain Hp-400) and ...[more]

PMID: 35036696

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The proteomic changes of GES1 infected by Helicobacter pylori

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2022-02-14 | PXD025281 | Pride

The proteomic of Helicobacter pylori OMVs

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