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Analysis of circ101093 binding proteins in A549 cells after RNA pull-down.

ABSTRACT: We used circular RNA 101093 and its antisense to perform RNA pull-down, and analyzed the peptides in blank group, antisense group and circular RNA 101093 group. The object of this group is to analyze circ101093-binding protein. Blank and antisense group are used as negative control group.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung

SUBMITTER: zhang xiao

LAB HEAD: Jiayi Wang

PROVIDER: PXD025575 | Pride | 2022-05-20

REPOSITORIES: Pride

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Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma.

Zhang Xiao X Xu Yunhua Y Ma Lifang L Yu Keke K Niu Yongjie Y Xu Xin X Shi Yi Y Guo Susu S Xue Xiangfei X Wang Yikun Y Qiu Shiyu S Cui Jiangtao J Wang Hong H Tian Xiaoting X Miao Yayou Y Meng Fanyu F Qiao Yongxia Y Yu Yongchun Y Wang Jiayi J

Cancer communications (London, England) 20220220 4

<h4>Background</h4>Resistance to ferroptosis, a regulated cell death caused by iron-dependent excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma (LUAD). Intracellular antioxidant systems are required for protection against ferroptosis. The purpose of the present study was to investigate whether and how extracellular system desensitizes LUAD cells to ferroptosis.<h4>Methods</h4>Established human lung fibroblasts MRC-5, WI38, and human LUAD H1650, PC9, H1975 ...[more]

PMID: 35184419

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