Human colorectal cancer LC-MS/MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Colon
SUBMITTER: 
Jiayi Hou
LAB HEAD: Jiayi Hou
PROVIDER: PXD025709 | Pride | 2023-10-24
REPOSITORIES: Pride
Publications
Histone crotonylation of peripheral blood mononuclear cells is a potential biomarker for diagnosis of colorectal cancer.
Hou Jia-Yi JY Li Ning N Wang Jie J Gao Li-Juan LJ Chang Jia-Song JS Cao Ji-Min JM
Epigenetics & chromatin 20230926 1
<h4>Background</h4>Blood-based tests have public appeal in screening cancers due to their minimally invasive nature, ability to integrate with other routine blood tests, and high compliance. This study aimed to investigate whether certain epigenetic modulation of peripheral blood mononuclear cells (PBMCs) could be a biomarker of colorectal cancer (CRC).<h4>Results</h4>Western blotting of histones in the PBMCs from 40 colorectal cancer patients and 40 healthy controls was performed to identify th ...[more]
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