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Characterisation of a FAK-proximal nuclear interactome

ABSTRACT: In addition to central functions in cell adhesion signalling, integrin-associated proteins have wider roles at sites distal to adhesion receptors. In experimentally defined adhesomes, we noticed that there is clear enrichment of proteins that localise to the nucleus, and conversely, we now report that nuclear proteomes contain a class of adhesome components that localise to the nucleus. We here defined a FAK-proximal subproteome that localises to the nucleus.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Skin

SUBMITTER: Adam Byron

LAB HEAD: Margaret Frame

PROVIDER: PXD025861 | Pride | 2022-06-01

REPOSITORIES: Pride

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