Proteomics

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Transcriptome and Proteomic Analysis Reveals Up-Regulation of Innate Immunity Related Genes Expression in Caprine Herpesvirus 1 Infected Madin Darby Bovine Kidney Cells

ABSTRACT: In order to further understanding the replication and pathogenesis of Caprine herpesvirus 1 (CpHV-1) and virus-host interactions. In this study, the proteomics of CpHV-1 infected Madin Darby bovine kidney (MDBK) cells was explored by using iTRAQ-LC-MS/MS technology.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Kidney

SUBMITTER: zeng liang  

LAB HEAD: Fei Hao

PROVIDER: PXD026014 | Pride | 2022-02-17

REPOSITORIES: Pride

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Transcriptome and Proteomic Analysis Reveals Up-Regulation of Innate Immunity-Related Genes Expression in Caprine Herpesvirus 1 Infected Madin Darby Bovine Kidney Cells.

Hao Fei F   Xie Xing X   Liu Maojun M   Mao Li L   Li Wenliang W   Na Woonsung W  

Viruses 20210702 7

Caprine herpesvirus 1 (CpHV-1) is a member of the alpha subfamily of herpesviruses, which is responsible for genital lesions and latent infections in goat populations worldwide. In this study, for the first time, the transcriptome and proteomics of CpHV-1 infected Madin Darby bovine kidney (MDBK) cells were explored using RNA-Sequencing (RNA-Seq) and isobaric tags for relative and absolute quantitation-liquid chromatography tandem mass spectrometry (iTRAQ-LC-MS/MS) technology, respectively. RNA-  ...[more]

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