Community detection from empirical kinase networks identifies new members of signalling pathways

ABSTRACT: We use phosphorylation sites to quantify the enrichment of kinase-kinase relationships in response to diferent kinase inhibitors, from which we construct weighted kinase networks, and assess whether the application of community detection algorithms to such networks can provide new insights on the inner workings of canonical signalling pathways

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Myeloblast, Peripheral Blood

DISEASE(S): Acute Myeloid Leukemia

SUBMITTER: Maruan Hijazi  

LAB HEAD: Pedro Cutillas

PROVIDER: PXD026039 | Pride | 2023-06-07

REPOSITORIES: Pride