Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Serum
SUBMITTER: Thomas Krüger
LAB HEAD: Axel A. Brakhage
PROVIDER: PXD026082 | Pride | 2022-04-04
REPOSITORIES: Pride
Wich Melissa M Greim Stephanie S Ferreira-Gomes Marta M Krüger Thomas T Kniemeyer Olaf O Brakhage Axel A AA Jacobsen Ilse D ID Hube Bernhard B Jungnickel Berit B
Virulence 20211201 1
<i>Candida albicans</i> is a common commensal on human mucosal surfaces, but can become pathogenic, e.g. if the host is immunocompromised. While neutrophils, macrophages and T cells are regarded as major players in the defense against pathogenic <i>C. albicans</i>, the role of B cells and the protective function of their antibodies are less well characterized. In this study, we show that human serum antibodies are able to enhance the association of human THP-1 monocyte-like cells with <i>C. albi ...[more]