Dataset Information
COVID-19 patient plasma exosome proteomics
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
SUBMITTER: 
Ni zhen
LAB HEAD: Guanghou Shui
PROVIDER: PXD026091 | Pride | 2021-05-19
REPOSITORIES: Pride
Dataset's files
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Publications
A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19.
Nature metabolism 20210622 7
Exosomes represent a subtype of extracellular vesicle that is released through retrograde transport and fusion of multivesicular bodies with the plasma membrane<sup>1</sup>. Although no perfect methodologies currently exist for the high-throughput, unbiased isolation of pure plasma exosomes<sup>2,3</sup>, investigation of exosome-enriched plasma fractions of extracellular vesicles can confer a glimpse into the endocytic pathway on a systems level. Here we conduct high-coverage lipidomics with an ...[more]
