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PfAP2-O Influences Virulence Gene Transcription and Sexual Development in Plasmodium falciparum

ABSTRACT: The project examined the function of the putative transcription factor PfAP2-O from Plasmodium falciparum. This factor besides an essential function in sexual stages also influences variant, virulence associated genes. In a pull down analysis, HA-tagged PfAP2-O was immunoprecipitated and proteins assoaciated were analysed and three differentially appearing protein bands were analysed.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Plasmodium Falciparum (isolate 3d7)

TISSUE(S): Blood

DISEASE(S): Plasmodium Falciparum Malaria

SUBMITTER: Gerhard Wunderlich

LAB HEAD: Gerhard Wunderlich

PROVIDER: PXD026237 | Pride | 2021-06-28

REPOSITORIES: Pride

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