Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

ABSTRACT: Here we use unbiased abundance proteomics and phosphoproteomics to assess global changes to host and viral proteins in Calu-3 cells at 10 and 24 hours post infection with either the B.1.1.7 UK variant or early-lineage SARS-CoV-2 viruses VIC and IC19.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Severe Acute Respiratory Syndrome Coronavirus 2

TISSUE(S): Lung, Epithelial Cell

SUBMITTER: Mehdi Bouhaddou  

LAB HEAD: Nevan J. Krogan

PROVIDER: PXD026302 | Pride | 2022-01-20

REPOSITORIES: Pride