Proteomics

Dataset Information

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Endometrial extracellular vesicle decidualization


ABSTRACT: Proper decidualization is vital in preparation for a potential embryo receptivity, placentation, menstrual health and subsequent endometrial regeneration. Given the importance of extracellular vesicles (EVs) in intercellular communication, and recently in embryo implantation and indicators of menstrual cycle and fertility, we investigated their role during decidualization. Overall, this study provides an insight into distinct variation in sEV composition depending upon the level of decidualization of endometrial stromal cells, with the signaling potential to coordinate endometrial health ranging from embryo implantation, facilitating placentation and subsequent endometrial regeneration.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Endometrial Stromal Cell, Endometrial Stroma

DISEASE(S): Disease Free

SUBMITTER: david greening  

LAB HEAD: David Greening

PROVIDER: PXD026342 | Pride | 2021-11-17

REPOSITORIES: Pride

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