Mouse 129SV submandibular salivary gland. -Male vs Female- and -Wildtype vs ERdj5 knockout-

ABSTRACT: In this study we have explored the effects of ERdj5 chaperone protein deletion in the proteome of 129SV mouse submandibular salivary glands. This knockout mouse model recapitulates many aspects of Sjögren’s Syndrome, including salivary gland inflammatory infiltrations, anti-nuclear autoantibodies and others (Apostolou et al., Front.Immunol.2019;10,506). Additionally, for 12SV wildtype animals we explore the proteome profile of the extensive sexual dimorphism observed in the submanidular glands of mice.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Submandibular Gland

DISEASE(S): Sjogren's Syndrome

SUBMITTER: Petros Moustardas  

LAB HEAD: Petros Moustardas

PROVIDER: PXD026424 | Pride | 2021-06-21

REPOSITORIES: Pride