Proteomics

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UV induced changes in proteome of rats plasma are reversed by dermally applied cannabidiol


ABSTRACT: The aim of this study was to analyze the changes in the proteomic profile of plasma from chronically UVA or UVB irradiated rats and define the effect on these changes of skin topically applied CBD.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Blood Plasma

SUBMITTER: Agnieszka Gęgotek  

LAB HEAD: Gegotek Agnieszka

PROVIDER: PXD026668 | Pride | 2022-02-17

REPOSITORIES: Pride

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Publications

UV induced changes in proteome of rats plasma are reversed by dermally applied cannabidiol.

Gęgotek Agnieszka A   Atalay Sinemyiz S   Skrzydlewska Elżbieta E  

Scientific reports 20211019 1


UV radiation is known to induce a multiple changes in the metabolism of skin-building cells, what can affect the functioning not only neighboring cells, but also, following signal transduction releasing into the blood vessels, the entire body. Therefore, the aim of this study was to analyze the proteomic disturbances occurred in plasma of chronically UVA/UVB irradiated rats and define the effect on these changes of skin topically applied cannabidiol (CBD). Obtained results showed significant cha  ...[more]

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