MiR141 Proteomic profile in Ovarian Cancer

ABSTRACT: Over the last two decades, mounting evidence has demonstrated the aberrant expression of miRNAs in different human malignancies, including ovarian carcinomas. In this study, we found that miR-141 were secreted by ovarian cancer cells and transferred to the stromal cells by exosomal pathway. To clarify the mechanisms that miR-141 remodeling stromal fibroblast and reprogramming the relevant signals, miR-141 were overexpressed in WPMY-1 and their respective scrambled control were send for proteomic analysis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Stromal Cell Of Ovarian Cortex

DISEASE(S): Malignant Neoplasm Of Ovary

SUBMITTER: Xueyu WANG  

LAB HEAD: Dr. David W. CHAN

PROVIDER: PXD026929 | Pride | 2023-03-11

REPOSITORIES: Pride