Proteomics

Dataset Information

0

Global quantitative proteomic analysis of aging Drosophila eyes


ABSTRACT: Wild-type Drosophila melanogaster expressing nuclear GFP-KASH fusion protein in photoreceptors for cell type-specific gene expression profiling (Rh1-Gal4>UAS-GFPKASH ; Genotype = w1118;; P{w+mC=[UAS-GFP-Msp300KASH}attP2, P{ry+t7.2=rh1-GAL4}3, ry506) were raised in 12:12h light:dark cycle at 25°C. Flies were aged for 10 or 40 days post-eclosion, and eyes were harvested from male flies for global quantitative proteomic analysis. Significantly changed proteins were identified that may contribute to age-associated retinal degeneration and loss of visual function in the aging Drosophila eye.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Drosophila Melanogaster (fruit Fly)

SUBMITTER: Aruna Wijeratne  

LAB HEAD: Vikki M. Weake

PROVIDER: PXD027090 | Pride | 2021-07-23

REPOSITORIES: Pride

Similar Datasets

2015-02-01 | E-GEOD-65325 | biostudies-arrayexpress
2015-05-08 | E-GEOD-67590 | biostudies-arrayexpress
2015-05-08 | E-GEOD-58854 | biostudies-arrayexpress
2023-04-27 | PXD034050 | Pride
2011-02-17 | E-GEOD-27344 | biostudies-arrayexpress
2021-11-25 | PXD027101 | Pride
2015-05-23 | E-GEOD-61361 | biostudies-arrayexpress
2021-09-09 | PXD021312 | Pride
2012-06-30 | E-GEOD-37148 | biostudies-arrayexpress
2020-02-24 | PXD015543 | Pride