Proteomics

Dataset Information

0

Pig metaproteome and mycotoxins


ABSTRACT: The effect of the mycotoxins deoxynivalenol (DON) and zearalenone (ZEN) on the gut microbiome of 15 weaners were analysed. Animals were fed for 28 days with low and high dosages of the toxins. Animals of the control group did not receive any mycotoxin-spiked feed. The gut metaproteome composition shifted due to the high dosages of the toxins compared to the control and low mycotoxin groups and it was also more similar between the animals that received high dosages of the mycotoxins.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Jejunum, Ileum

SUBMITTER: Jana Seifert  

LAB HEAD: Prof. Jana Seifert

PROVIDER: PXD027185 | Pride | 2021-09-07

REPOSITORIES: Pride

altmetric image

Publications

Metaproteomics Reveals Alteration of the Gut Microbiome in Weaned Piglets Due to the Ingestion of the Mycotoxins Deoxynivalenol and Zearalenone.

Saenz Johan S JS   Kurz Alina A   Ruczizka Ursula U   Bünger Moritz M   Dippel Maximiliane M   Nagl Veronika V   Grenier Bertrand B   Ladinig Andrea A   Seifert Jana J   Selberherr Evelyne E  

Toxins 20210821 8


The ingestion of mycotoxins can cause adverse health effects and represents a severe health risk to humans and livestock. Even though several acute and chronic effects have been described, the effect on the gut metaproteome is scarcely known. For that reason, we used metaproteomics to evaluate the effect of the mycotoxins deoxynivalenol (DON) and zearalenone (ZEN) on the gut microbiome of 15 weaned piglets. Animals were fed for 28 days with feed contaminated with different concentrations of DON  ...[more]

Similar Datasets

2022-03-01 | PXD016388 | Pride
2019-08-16 | PXD010134 | Pride
2010-05-07 | E-GEOD-19227 | biostudies-arrayexpress
2022-08-22 | PXD032997 | Pride
2010-03-01 | GSE19227 | GEO
2019-12-03 | PXD014864 | Pride
2021-11-04 | PXD025887 | Pride
2020-07-21 | PXD015934 | Pride
2022-11-21 | E-NASC-52 | biostudies-arrayexpress
2022-07-29 | PXD024845 | Pride