Proteomic characterization of primary and brain metastatic lung adenocarcinomas in a well-defined patient cohort

ABSTRACT: Lung adenocarcinoma (LADC) is the most common subtype of non-small cell lung cancer (NSCLC). One major feature of disease progression is the metastatic spread to the central nervous system (CNS). Treatment regimens for brain metastases are limited, thus distant metastases remain the leading cause of tumour-associated deaths globally. The central aim of this paper was to investigate the differences of LADC and brain metastases with reference to fast and slowly progressing patients. Additionally, we elucidated the differences between patients with single versus multiple brain metastases.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain, Lung

DISEASE(S): Lung Adenocarcinoma

SUBMITTER: Nicole Woldmar  

LAB HEAD: Gyorgy Marko-Varga

PROVIDER: PXD027259 | Pride | 2023-03-11

REPOSITORIES: Pride