Proteome-Level Functional Redundancy in the Human Gut Microbiome

ABSTRACT: Here, we quantify the proteome-level functional redundancy in the human gut microbiome using metaproteomics and network approaches.In particular, we used an ultra-deep metaproteomics approach based on high-pH reverse phase fractionation. The data analysis revealed high protein-level functional redundancy and high nestedness in proteomic content networks - bipartite graphs that connect taxa with their expressed functions.

INSTRUMENT(S):

ORGANISM(S): Human Gut Metagenome

TISSUE(S): Gut

SUBMITTER: Leyuan Li  

LAB HEAD: Daniel Figeys

PROVIDER: PXD027297 | Pride | 2023-06-08

REPOSITORIES: Pride