Identify the specific binding partners of cytosolic TDP-43 WT and TDP-43ΔCR

ABSTRACT: To investigate how translation changed as a function of TDP-43 CR loss, mass spectrometry (MS) based approach was performed to monitor the dynamics of TDP-43-associated protein complexes in response to CR deletion using TDP-43 knockout HEK293 cells expressing strep tagged wild type TDP-43 (TDP-43WT) or TDP-43ΔCR mutant.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

SUBMITTER: Ju Gao  

LAB HEAD: Xinglong Wang

PROVIDER: PXD027494 | Pride | 2022-05-20

REPOSITORIES: Pride