Human embryo proteome reprogramming by endometrial extracellular vesicles
Ontology highlight
ABSTRACT: - Endometrial sEV protein cargo are hormonally regulated – EP treated sEVs are enriched in key players of embryo implantation - Endometrial sEVs are taken up by recipient trophectoderm cells - Endometrial EP-sEVs (or secretory phase sEVs) promote trophectoderm cell invasion via MAPK signalling pathway - Invasion-related proteins are enriched on Tsc cell surface following EP-sEV treatment
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Glandular Cell Of Endometrium, Embryonic Stem Cell
DISEASE(S): Disease Free
SUBMITTER: david greening
LAB HEAD: David Greening
PROVIDER: PXD027642 | Pride | 2021-11-17
REPOSITORIES: Pride
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