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Proteome and phosphoproteome analysis in chronically MTOR-deficient clones

ABSTRACT: Shotgun-proteomics and phosphoproteomics analysis of clonal pancreatic tumor cell lines upon long-term ablation of the energy master kinase regualator mTOR

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Primary Cell Line Cell

DISEASE(S): Pancreatic Cancer

SUBMITTER: Stella Koutsouli

LAB HEAD: Prof. Maria Robles, PhD

PROVIDER: PXD027779 | Pride | 2022-05-20

REPOSITORIES: Pride

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Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition.

Schneeweis Christian C Hassan Zonera Z Ascherl Katja K Wirth Matthias M Koutsouli Stella S Orben Felix F Krauß Lukas L Schneider Carolin C Öllinger Rupert R Krämer Oliver H OH Rad Roland R Reichert Maximilian M Robles Maria S MS Saur Dieter D Schneider Günter G

Cancer communications (London, England) 20220307 4

PMID: 35253411

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