A proximity interactome map of the VAC14-FIG4 complex using BioID

ABSTRACT: Conversion between phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate on endosomal membranes is critical for maturation of early endosomes to late endosomes/lysosomes, and is regulated by the PIKfyve-Vac14-Fig4 complex. In this study, we screened for the cellular interactome of Vac14 and Fig4 using proximity-dependent biotin labelling (BioID) in 293T cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Shirley Qiu  

LAB HEAD: Dr. Marceline Côté

PROVIDER: PXD027917 | Pride | 2021-11-03

REPOSITORIES: Pride