Human HEK293T cells LC-MS/MS (Gel-based proteomics)

ABSTRACT: Fanconi Anemia (FA) pathway is essential for the repair of inter-strand crosslink (ICLs). ICL induces stalled replication forks and triggers activation of FA pathway for efficient ICL repair. Given that stalled replication fork is proximal to ICLs sites, fork-associated proteins may likely coordinate with FA factors to rapidly sense ICLs for activation of FA signaling. We will use LC-MS/MS to identify such proteins that participated in the ICL repairs.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture, Kidney

SUBMITTER: YI ZHANG  

LAB HEAD: Wenge Zhu

PROVIDER: PXD028246 | Pride | 2023-05-10

REPOSITORIES: Pride