Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis

ABSTRACT: Increasing studies suggested the treatment potential of mesenchymal stem cells in variety diseases. Evidence showed that MSCs could promote injured tissue repair and improve disease mortality. These indicated that MSC transplantation may be an ideal candidate for cholestasis treatment.We found that MenSC transplantation could significantly improve the symptoms and pathological changes of DDC-induced cholestasis liver injury in mice.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Liver

SUBMITTER: Y Y  

LAB HEAD: Ya Yang

PROVIDER: PXD028425 | Pride | 2022-02-16

REPOSITORIES: Pride