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Comparative proteomics of Eubacterium maltosivorans: reveal of propionogenic metabolism and bacterial microcompartments in a human intestinal bacterium.

ABSTRACT: This study was conducted in order to explore proteins involved in 1,2-propanediol utilization and microcompartments formation of E. maltosivorans. We also identified the maltose specific ABC transporter in E. maltosivorans when it was grown with this substrate.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Eubacterium Maltosivorans

SUBMITTER: Sjef Boeren

LAB HEAD: Sjef Boeren

PROVIDER: PXD028575 | Pride | 2022-08-12

REPOSITORIES: Pride

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Comparative genomics and proteomics of Eubacterium maltosivorans: functional identification of trimethylamine methyltransferases and bacterial microcompartments in a human intestinal bacterium with a versatile lifestyle.

Feng Yuan Y Bui Thi Phuong Nam TPN Stams Alfons J M AJM Boeren Sjef S Sánchez-Andrea Irene I de Vos Willem M WM

Environmental microbiology 20220102 1

Eubacterium maltosivorans YIT is a human intestinal isolate capable of acetogenic, propionogenic and butyrogenic growth. Its 4.3-Mb genome sequence contains coding sequences for 4227 proteins, including 41 different methyltransferases. Comparative proteomics of strain YIT showed the Wood-Ljungdahl pathway proteins to be actively produced during homoacetogenic growth on H2 and CO2 while butyrogenic growth on a mixture of lactate and acetate significantl ...[more]

PMID: 34978130

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