Proteomics

Dataset Information

0

Mouse skeletal muscle nano-HPLC-MS/MS


ABSTRACT: differential proteomics regulated by ITGB6 in sakeletal muscle satellite cells

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Stem Cell, Cell Culture

SUBMITTER: Weiya Zhang  

LAB HEAD: Weiya Zhang

PROVIDER: PXD028650 | Pride | 2022-08-12

REPOSITORIES: Pride

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Publications

ITGβ6 Facilitates Skeletal Muscle Development by Maintaining the Properties and Cytoskeleton Stability of Satellite Cells.

Zhang Hong H   Liu Yuan Y   Li Cencen C   Zhang Weiya W  

Life (Basel, Switzerland) 20220621 7


Integrin proteins are important receptors connecting the intracellular skeleton of satellite cells and the extracellular matrix (ECM), playing an important role in the process of skeletal muscle development. In this research, the function of ITGβ6 in regulating the differentiation of satellite cells was studied. Transcriptome and proteome analysis indicated that <i>Itgβ6</i> is a key node connecting ECM-related proteins to the cytoskeleton, and it is necessary for the integrity of the membrane s  ...[more]

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