Protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls

ABSTRACT: Using liquid chromatography combined with tandem mass spectrometry, we want to use quantitative proteomics of CD4+ T cells from relapsing-remitting MS (RRMS) patients and healthy controls. Cells were left unstimulated or stimulated through the T cell receptor (TCR) in vitro allowing us to disentangle potential CD4+ T cell specific differences induced by T cell activation This will provide novel insights into disease mechanisms of MS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cd4 Molecule, Blood

DISEASE(S): Disease Free,Relapsing-remitting Multiple Sclerosis

SUBMITTER: Tone Berge  

LAB HEAD: Tone Berge

PROVIDER: PXD028702 | Pride | 2022-08-01

REPOSITORIES: Pride