Global Proteomic Analysis of Lysine lactylation in HMC3 cells under Normoxia or Hypoxia

ABSTRACT: This project carried out a quantitative study of lactylation in HMC3 Cell Line. In order to ensure a high degree of credibility of the results, we used the standard of localization probability>0.75 to filter the authentication data. In this study, a total of 3093 lactylation sites located on 1270 proteins were identified, of which 1601 sites of 751 proteins contain quantitative information. Subsequently, we carried out a systematic bioinformatics analysis of proteins containing quantitative information sites, including protein annotation, functional classification, functional enrichment and cluster analysis based on functional enrichment.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Microglial Cell

DISEASE(S): Retinopathy Of Prematurity

SUBMITTER: Shengping Hou  

LAB HEAD: Shengping Hou

PROVIDER: PXD028737 | Pride | 2023-03-28

REPOSITORIES: Pride