Proteomics

Dataset Information

0

I.e.Human Veinou malformation.iTraq/TMT


ABSTRACT: Proteomics and high connotation functional gene screening (HCS) were used to screen key functional genes that play important roles in the pathogenesis of venous malformation.

INSTRUMENT(S): LCQ Classic

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Vascular System

SUBMITTER: Song Wang  

LAB HEAD: i.e.Jianhai Bi

PROVIDER: PXD028848 | Pride | 2022-02-16

REPOSITORIES: Pride

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Publications

Identification of ACTA2 as a Key Contributor to Venous Malformation.

Wang Song S   Zhou Zifu Z   Li Jing J   Wang Yu Y   Li Hongwen H   Lv Renrong R   Xu Guangqi G   Zhang Jian J   Bi Jianhai J   Huo Ran R  

Frontiers in cell and developmental biology 20211108


<b>Objectives:</b> Proteomics and high connotation functional gene screening (HCS) were used to screen key functional genes that play important roles in the pathogenesis of venous malformation. Furthermore, this study was conducted to analyze and explore their possible functions, establish a gene mutation zebrafish model, and perform a preliminary study to explore their possible pathogenic mechanisms in venous malformation. <b>Methods:</b> Pathological and normal tissues from patients with disse  ...[more]

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