Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
DISEASE(S): Lung Cancer
SUBMITTER: Bent Honoré
LAB HEAD: Bent Honoré
PROVIDER: PXD028885 | Pride | 2022-04-04
REPOSITORIES: Pride
Pedersen Shona S Jensen Katrine Papendick KP Honoré Bent B Kristensen Søren Risom SR Pedersen Camilla Holm CH Szejniuk Weronika Maria WM Maltesen Raluca Georgiana RG Falkmer Ursula U
Clinical proteomics 20220107 1
<h4>Background</h4>Early detection of small cell lung cancer (SCLC) crucially demands highly reliable markers. Growing evidence suggests that extracellular vesicles carry tumor cell-specific cargo suitable as protein markers in cancer. Quantitative proteomic profiling of circulating microvesicles and exosomes can be a high-throughput platform for discovery of novel molecular insights and putative markers. Hence, this study aimed to investigate proteome dynamics of plasma-derived microvesicles an ...[more]