Proteomics

Dataset Information

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Human HEK293 Gemin5 clinical variants LC-MSMS


ABSTRACT: Identification of cellular proteins interacting with Gemin5 variants found in patients with neurological disorders. P85 C-terminal fragment of Gemin5 has been used to purify the protein complexes associated by Tandem Affinity Purification. The study has been performed using two biological replicates of each bait protein: p85-WT, the dimerization mutant p85-A951E, and the clinical variants p85-R1016C, p85-D1019E and p85-L1367P.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Rosario Francisco-Velilla  

LAB HEAD: ENCARNACION MARTINEZ-SALAS

PROVIDER: PXD028959 | Pride | 2022-04-06

REPOSITORIES: Pride

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