Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Sergey Vakhrushev
LAB HEAD: Sergey Vakhrushev
PROVIDER: PXD028982 | Pride | 2022-02-17
REPOSITORIES: Pride
Sun Lingbo L Konstantinidi Andriana A Ye Zilu Z Nason Rebecca R Zhang Yuecheng Y Büll Christian C Kahl-Knutson Barbro B Hansen Lars L Leffler Hakon H Vakhrushev Sergey Y SY Yang Zhang Z Clausen Henrik H Narimatsu Yoshiki Y
The Journal of biological chemistry 20211224 2
The human genome contains at least 35 genes that encode Golgi sulfotransferases that function in the secretory pathway, where they are involved in decorating glycosaminoglycans, glycolipids, and glycoproteins with sulfate groups. Although a number of important interactions by proteins such as selectins, galectins, and sialic acid-binding immunoglobulin-like lectins are thought to mainly rely on sulfated O-glycans, our insight into the sulfotransferases that modify these glycoproteins, and in par ...[more]