Proteomics

Dataset Information

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Influenza-derived peptide presentation by HLA-A*11:01

ABSTRACT: Analysis of the immunopeptidome of Human Leukocyte Antigen (HLA)-A*11:01 during influenza infection. Analyses were performed using the Class I reduced C1R cell line transfected with the HLA class I allele HLA-A*11:01.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood

SUBMITTER: Patricia Illing  

LAB HEAD: Anthony W. Purcell

PROVIDER: PXD028985 | Pride | 2022-02-15

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
IAV_Search1.mzid.gz Mzid
IAV_search2.mzid.gz Mzid
IBV_search1.mzid.gz Mzid
P2PI20181029_pilling_A11_rep1_Pool1.mgf Mgf
P2PI20181029_pilling_A11_rep1_Pool1.raw Raw
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Publications

HLA-A*11:01 is one of the most prevalent human leukocyte antigens (HLAs), especially in East Asian and Oceanian populations. It is also highly expressed in Indigenous people who are at high risk of severe influenza disease. As CD8+ T cells can provide broadly cross-reactive immunity to distinct influenza strains and subtypes, including influenza A, B and C viruses, understanding CD8+ T cell immunity to influenza viruses across prominent HLA types is needed to rationally design a universal influe  ...[more]

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