Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Michele Costanzo
LAB HEAD: Michele Costanzo
PROVIDER: PXD029012 | Pride | 2021-12-20
REPOSITORIES: Pride
Manganelli Valeria V Salvatori Illari I Costanzo Michele M Capozzi Antonella A Caissutti Daniela D Caterino Marianna M Valle Cristiana C Ferri Alberto A Sorice Maurizio M Ruoppolo Margherita M Garofalo Tina T Misasi Roberta R
Cells 20211202 12
Neuroglobin (NGB) is an O<sub>2</sub>-binding globin mainly expressed in the central and peripheral nervous systems and cerebrospinal fluid. Previously, it was demonstrated that NGB overexpression protects cells from hypoxia-induced death. To investigate processes promoted by NGB overexpression, we used a cellular model of neuroblastoma stably overexpressing an NGB-FLAG construct. We used a proteomic approach to identify the specific profile following NGB overexpression. To evaluate the role of ...[more]