Proteomics

Dataset Information

0

Citrullinated epitopes identified on tumor MHC class II by peptide elution stimulate both regulatory and Th1 responses and require careful selection for optimal tumor therapy


ABSTRACT: In this manuscript, we outline the identification of citrullinated peptide epitopes presented on the surface of tumor cells that can be targeted for tumor therapy. Peptide elution from MHC is a useful tool in the identification of novel targets and has been used by many in immunotherapy strategies. Here we describe the identification of post-translationally modified citrullinated peptides through elution from MHC class II molecules.

INSTRUMENT(S): LTQ Orbitrap XL

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Ana Marcu  

LAB HEAD: Lindy G Durrant

PROVIDER: PXD029029 | Pride | 2021-11-24

REPOSITORIES: Pride

Similar Datasets

2023-02-27 | PXD033383 | Pride
2023-02-20 | PXD036811 | Pride
2023-04-07 | PXD034773 | Pride
2020-05-27 | PXD016060 | Pride
2020-11-11 | PXD012771 | Pride
2018-03-09 | PXD007935 | Pride
2023-11-21 | PXD038782 | Pride
2020-01-15 | PXD012797 | Pride
2020-11-30 | PXD017824 | Pride
2019-01-02 | PXD011723 | Pride