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Urinary proteins in dogs suffering leishmaniasis

ABSTRACT: This study is aimed at the description of the urinary proteome of dogs with of glomerulonephritis secondary to leishmaniasis, compare it with human proteome and identify possible new biomarkers for glomerular disease in leishmaniasis

INSTRUMENT(S): Agilent MassHunter format

ORGANISM(S): Canis Familiaris (dog) (canis Lupus Familiaris)

TISSUE(S): Urine

DISEASE(S): Visceral Leishmaniasis

SUBMITTER: FERNANDO JUAN PEÑA VEGA

LAB HEAD: LABORATORIO DE PATOLOGÍA CLÍNICA UNIVERSIDAD DE EXTREMADURA

PROVIDER: PXD029165 | Pride | 2022-08-11

REPOSITORIES: Pride

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Urinary proteome of dogs with renal disease secondary to leishmaniosis.

González Mario A MA Barrera-Chacón Rafael R Peña Fernando J FJ Fernández-Cotrina Javier J Robles Nicolás R NR Pérez-Merino Eva M EM Martín-Cano Francisco E FE Duque Francisco J FJ

Research in veterinary science 20220625

Canine leishmaniosis is frequently associated with the development of renal disease. Its pathogenesis is complex and not fully understood. For this reason, this study aimed to describe the urinary proteome, and identify possible new biomarkers in dogs with kidney disease secondary to leishmaniosis. Urine samples were collected from 20 dogs, 5 from healthy dogs, and 15 from stages Leishvet III and IV. Urine samples were analyzed by UHPLC-MS/MS. The data are available via ProteomeXchange with iden ...[more]

PMID: 35777279

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