Alternative polyadenylation factor CPSF6 regulates temperature compensation of the mammalian circadian clock

ABSTRACT: A defining property of circadian clocks is temperature compensation, characterized by the resilience of circadian free-running periods against changes in environmental temperature.We quantify global changes in 3´UTR length as well as gene and protein expression between wild type and CPSF6 knock-down cells and their dependency on temperature.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

DISEASE(S): Osteosarcoma

SUBMITTER: Maria Robles  

LAB HEAD: Prof. Dr. Charo Robles

PROVIDER: PXD029343 | Pride | 2023-05-23

REPOSITORIES: Pride