Proteomics

Dataset Information

Complexome profiling of mitochondria to study organismic consequences of aging in Podospora anserina

ABSTRACT: Podospora anserina is an established aging model with a strong mitochondrial etiology of aging. Here we performed a complexome analysis of isolated mitochondria to study age-related changes of assembled mitochondrial protein complexes. The analysis revealed prominent age-related alterations in oxidative phosphorylation (OXPHOS) and the induction of non-mitochondrial salvage pathways.

INSTRUMENT(S):

ORGANISM(S): Podospora Anserina

SUBMITTER: Ilka Wittig  

LAB HEAD: Heinz D. Osiewacz

PROVIDER: PXD029352 | Pride | 2022-02-22

REPOSITORIES: Pride

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