Digoxin induces astrocyte activation into a human in vitro astrocyte model
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ABSTRACT: In this study we have evaluated the effect of digoxin in human astrocytes. Our results have shown that non-cytotoxic concentration of digoxin is able to induce astrocytes activation, by affecting cytoskeleton proteins, increasing the expression of pro-inflammatory genes and altering energy metabolism pathways between other mechanisms.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Astrocyte
SUBMITTER:
Tatjana Vujic
LAB HEAD: Jean-Charles Sanchez
PROVIDER: PXD029370 | Pride | 2023-03-11
REPOSITORIES: Pride
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