Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Eclipse
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Joao Paulo
LAB HEAD: Joao A. Paulo
PROVIDER: PXD029458 | Pride | 2022-01-06
REPOSITORIES: Pride
Navarrete-Perea Jose J Liu Xinyue X Rad Ramin R Gygi Jeremy P JP Gygi Steven P SP Paulo Joao A JA
Proteomics 20220114 7
Reporter ion interference remains a limitation of isobaric tag-based sample multiplexing. Advances in instrumentation and data acquisition modes, such as the recently developed real-time database search (RTS), can reduce interference. However, interference persists as does the need to benchmark upstream sample preparation and data acquisition strategies. Here, we present an updated Triple yeast KnockOut (TKO) standard as well as corresponding upgrades to the TKO viewing tool (TVT2.5, http://tko. ...[more]