Lysosomal damage proteomics in HeLa cells
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ABSTRACT: To identify ubiquitylation targets following lysosomal damage in HeLa cells treated with LLOMe we performed quantitative ubiquitin-remmnant (diGly) profilig coupled to mass spectrometry (MS). In addition, we performed APEX2-based proximity biotinylation followed by MS analysis to identify proximity partners of one of the ubiquitylation targets (CNN2).
INSTRUMENT(S): Q Exactive HF, LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell
DISEASE(S): Cervix Carcinoma
SUBMITTER: Christian Behrends
LAB HEAD: Christian Behrends
PROVIDER: PXD029926 | Pride | 2022-06-23
REPOSITORIES: Pride
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