The E3 ubiquitin ligase adaptor cereblon targets the C-terminal cyclic imide degron

ABSTRACT: We identify cyclic imides, previously overlooked post-translation modifications, across different tissues (red blood cells and bovine lens) and human-derived cell lines and found that these modifications are globally regulated by cereblon.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Bos Taurus (bovine)

TISSUE(S): Erythrocyte, Eye, Cell Suspension Culture, Plasma Cell, Early Embryonic Cell, Cell Culture, Blood

SUBMITTER: Christina Woo  

LAB HEAD: Christina Woo

PROVIDER: PXD030091 | Pride | 2022-07-28

REPOSITORIES: Pride