LC-MS/MS identification of interactors of Interleukin-1 Receptor Associated Kinase 3 (IRAK3)

ABSTRACT: Imterleukin-1 Receptor Associated Kinase 3 (IRAK3) acts as a negative regulator of interleukin-1 receptor and Toll-like receptors signalling by preventing dissociation of IRAKs from myddosome complex, therefore disabling production of proinflammatory cytokines. Since the molecular mode of IRAK3 action remains unclear, a large scale protein-protein interaction study has been undertaken to identify interactors of IRAK3 in human monocytes.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Monocyte

SUBMITTER: Ilona Turek  

LAB HEAD: Helen Ruth Irving

PROVIDER: PXD030321 | Pride | 2026-08-23

REPOSITORIES: Pride