Proteomic study of baicalein effects on LPS-primed BV2 microglia

ABSTRACT: To comprehensively study the intracellular signaling changes and explore the underlying mechanisms of baicalein-mediated microglial responses, we employed systemic proteomic approach, using target-free SWATH mass spectra (SWATH-MS), focusing on intracellular proteins. BV2 cells were treated with LPS followed by the addition of vehicle or baicalein and they were cultured for a total of 48 hours before being collected for proteomic analysis.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Microglial Cell Activation

DISEASE(S): Retinal Degeneration

SUBMITTER: Li PAN  

LAB HEAD: Chi-Wai Do

PROVIDER: PXD030447 | Pride | 2022-02-14

REPOSITORIES: Pride