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Proteomic analysis of somatosensory cortex of Pten haploinsufficient mice

ABSTRACT: To discover differentially expressed proteins in somatosensory cortex of Pten haploinsufficient mice at adolescence (P30). Result reveals signatures of perturbation of dendritic spine development, keratinization and hamartoma. These are collectively respresentating molecular perturbation of neuropathology of PTEN Harmatoma Tumor Syndrome (PHTS).

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

SUBMITTER: Stanley Cheung

LAB HEAD: Andrew M. Chan

PROVIDER: PXD030573 | Pride | 2023-04-26

REPOSITORIES: Pride

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