Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF-X
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Oliver Popp
LAB HEAD: Philipp Mertins
PROVIDER: PXD030785 | Pride | 2022-01-17
REPOSITORIES: Pride
Pekayvaz Kami K Leunig Alexander A Kaiser Rainer R Joppich Markus M Brambs Sophia S Janjic Aleksandar A Popp Oliver O Nixdorf Daniel D Fumagalli Valeria V Schmidt Nora N Polewka Vivien V Anjum Afra A Knottenberg Viktoria V Eivers Luke L Wange Lucas E LE Gold Christoph C Kirchner Marieluise M Muenchhoff Maximilian M Hellmuth Johannes C JC Scherer Clemens C Rubio-Acero Raquel R Eser Tabea T Deák Flora F Puchinger Kerstin K Kuhl Niklas N Linder Andreas A Saar Kathrin K Tomas Lukas L Schulz Christian C Wieser Andreas A Enard Wolfgang W Kroidl Inge I Geldmacher Christof C von Bergwelt-Baildon Michael M Keppler Oliver T OT Munschauer Mathias M Iannacone Matteo M Zimmer Ralf R Mertins Philipp P Hubner Norbert N Hoelscher Michael M Massberg Steffen S Stark Konstantin K Nicolai Leo L
Nature communications 20220223 1
The antiviral immune response to SARS-CoV-2 infection can limit viral spread and prevent development of pneumonic COVID-19. However, the protective immunological response associated with successful viral containment in the upper airways remains unclear. Here, we combine a multi-omics approach with longitudinal sampling to reveal temporally resolved protective immune signatures in non-pneumonic and ambulatory SARS-CoV-2 infected patients and associate specific immune trajectories with upper airwa ...[more]