Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite, Q Exactive
ORGANISM(S): Cancer
TISSUE(S): Cervical Squamo-columnar Junction
DISEASE(S): Cervical Cancer
SUBMITTER: Yue He
LAB HEAD: Yue-Mei Wu
PROVIDER: PXD030885 | Pride | 2022-05-20
REPOSITORIES: Pride
BMC cancer 20220414 1
<h4>Background</h4>To investigate the mechanism by which apolipoprotein A1 (APOA1) enhances the resistance of cervical squamous carcinoma to platinum-based chemotherapy.<h4>Methods</h4>Two cervical squamous carcinoma cell lines (SiHa and Caski) overexpressing APOA1 were constructed, treated with carboplatin, and compared to normal control cells.<h4>Results</h4>In both SiHa and Caski cell lines, the clone-forming ability of CBP-treated cells was lower than that of untreated cells, and the change ...[more]