Dataset Information
Human nasopharyngeal cancer cell HONE1 FOXP1 immunoprecipitates LC-MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Nasopharyngeal Epithelial Cell, Cell Culture
DISEASE(S): Neck Carcinoma
SUBMITTER: 
zhaoyang zeng
LAB HEAD: Zhaoyang Zeng, Wei Xiong
PROVIDER: PXD031014 | Pride | 2022-04-04
REPOSITORIES: Pride
Publications
EBV miRNAs BART11 and BART17-3p promote immune escape through the enhancer-mediated transcription of PD-L1.
Nature communications 20220214 1
Epstein-Barr virus (EBV) is reportedly the first identified human tumor virus, and is closely related to the occurrence and development of nasopharyngeal carcinoma (NPC), gastric carcinoma (GC), and several lymphomas. PD-L1 expression is elevated in EBV-positive NPC and GC tissues; however, the specific mechanisms underlying the EBV-dependent promotion of PD-L1 expression to induce immune escape warrant clarification. EBV encodes 44 mature miRNAs. In this study, we find that EBV-miR-BART11 and E ...[more]
