Differentiation of human induced pluripotent stem cells into induced motor neurons
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ABSTRACT: Characterisation of induced motor neurons (iMN) generated from human induced pluripotent stem cells (hiPSC, hPSCreg name BIHi005-A) using doxycycline inducible expression of Ngn2, Isl1 and Lhx3. While this method of iMN generation has been described before (REF: doi.org/10.1002/cpcb.51), no extensive characterisation of the transcriptome and proteome throughout the differentiation process or of the mature neurons has been undertaken so far.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Pluripotent Stem Cell, Neuron, Motor Neuron
SUBMITTER:
Tommaso Mari
LAB HEAD: Matthias Selbach
PROVIDER: PXD031066 | Pride | 2025-11-24
REPOSITORIES: Pride
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