Proteomics

Dataset Information

0

Pythium insidiosum protein identification


ABSTRACT: Pythiosis is a deadly infectious disease of humans and animals living in tropical and subtropical countries. The causative agent is the oomycete Pythium insidiosum. Treatment of pythiosis is challenging. Therefore, protein profiling could generate the important information for further drug development.

INSTRUMENT(S): Bruker Daltonics micrOTOF series

ORGANISM(S): Pythium Sp. Pv So7

SUBMITTER: onrapak reamtong  

LAB HEAD: Onrapak Reamtong

PROVIDER: PXD031111 | Pride | 2022-06-09

REPOSITORIES: Pride

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Publications

Secretome Profiling by Proteogenomic Analysis Shows Species-Specific, Temperature-Dependent, and Putative Virulence Proteins of <i>Pythium insidiosum</i>.

Krajaejun Theerapong T   Rujirawat Thidarat T   Lohnoo Tassanee T   Yingyong Wanta W   Sae-Chew Pattarana P   Reamtong Onrapak O   Kittichotirat Weerayuth W   Patumcharoenpol Preecha P  

Journal of fungi (Basel, Switzerland) 20220520 5


In contrast to most pathogenic oomycetes, which infect plants, <i>Pythium insidiosum</i> infects both humans and animals, causing a difficult-to-treat condition called pythiosis. Most patients undergo surgical removal of an affected organ, and advanced cases could be fetal. As a successful human/animal pathogen, <i>P. insidiosum</i> must tolerate body temperature and develop some strategies to survive and cause pathology within hosts. One of the general pathogen strategies is virulence factor se  ...[more]

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